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乙醇对足月催产素诱导分娩的抑制作用。

The inhibitory effect of ethanol on oxytocin-induced labor at term.

作者信息

Lauersen N H, Wilson K H, Fuchs F F

出版信息

J Reprod Med. 1981 Nov;26(11):547-50.

PMID:7338873
Abstract

Intravenous ethanol infusion significantly reduced oxytocin-induced uterine activity in pregnant patients at term. The dose response to oxytocin was linear when plotted log2 x in all patients studied, and the line was shifted to the right by alcohol, but the slope remained essentially unchanged. These results suggest that alcohol directly inhibits the effect of oxytocin on the myometrium, although the possibility of some central inhibition of oxytocin release cannot be discounted.

摘要

静脉输注乙醇可显著降低足月妊娠患者中缩宫素诱导的子宫活动。在所有研究的患者中,以log2 x作图时,对缩宫素的剂量反应呈线性,且该线因酒精作用而右移,但斜率基本保持不变。这些结果表明,酒精直接抑制缩宫素对子宫肌层的作用,尽管不能排除对缩宫素释放存在某种中枢抑制作用的可能性。

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