Nagel G A, Scherpe A
Langenbecks Arch Chir. 1981;355:77-80. doi: 10.1007/BF01286816.
In esophageal carcinoma chemotherapeutic agents such as bleomycin, methotrexate, cisplatin, VP-16, and vindesine produce remission rates up to 30%. Combination chemotherapy resulting in remission rates of about 50% has so far been insufficiently tested. Selection of patients with favorable prognostic criteria is mandatory for optimal treatment results. A combined modality approach is promising but needs further evaluation. The FAM regimen is recommended for the routine treatment of inoperable stomach carcinoma. The specific problems of upper gastrointestinal tract cancer chemotherapy are discussed.
在食管癌中，博来霉素、甲氨蝶呤、顺铂、依托泊苷和长春地辛等化疗药物的缓解率可达30%。目前，缓解率约为50%的联合化疗尚未得到充分测试。为了获得最佳治疗效果，必须选择具有良好预后标准的患者。综合治疗方法很有前景，但需要进一步评估。FAM方案推荐用于不可切除胃癌的常规治疗。本文讨论了上消化道癌化疗的具体问题。
