Chemical basis for diversity in antibody specificity analysed by hapten binding to monoclonal anti-4-hydroxy-3-nitrophenacetyl (NP) immunoglobulins. - Suppr | 超能文献

Chemical basis for diversity in antibody specificity analysed by hapten binding to monoclonal anti-4-hydroxy-3-nitrophenacetyl (NP) immunoglobulins.

作者信息

Mariuzza R, Strand M

出版信息

Mol Immunol. 1981 Sep;18(9):847-55. doi: 10.1016/0161-5890(81)90006-7.

DOI:10.1016/0161-5890(81)90006-7

Abstract

摘要

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Chemical basis for diversity in antibody specificity analysed by hapten binding to monoclonal anti-4-hydroxy-3-nitrophenacetyl (NP) immunoglobulins.

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Immunochemical properties of some monoclonal IgE antibodies to 4-hydroxy-3-nitrophenylacetyl (NP).一些针对4-羟基-3-硝基苯乙酰（NP）的单克隆IgE抗体的免疫化学特性。

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Genetic basis for altered idiotype expression in the hyperimmune response to (4-hydroxy-3-nitrophenyl)acetyl hapten.对（4-羟基-3-硝基苯基）乙酰半抗原超免疫反应中独特型表达改变的遗传基础。

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4-Hydroxy-3-nitro-phenylacetyl (NP)-specific T cell hybridomas.4-羟基-3-硝基苯乙酰（NP）特异性T细胞杂交瘤

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Specificity change of antibody to (4-hydroxy-3-nitrophenyl)acetyl haptens by somatic hypermutation.通过体细胞超突变对（4-羟基-3-硝基苯基）乙酰半抗原的抗体特异性变化

J Biochem. 1987 Dec;102(6):1337-43. doi: 10.1093/oxfordjournals.jbchem.a122179.

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Low affinity of kappa chain bearing (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific antibodies in the primary antibody repertoire of C57BL/6 mice may explain lambda chain dominance in primary anti-NP responses.在C57BL/6小鼠的初始抗体库中，带有（4-羟基-3-硝基苯基）乙酰基（NP）特异性抗体的κ链亲和力较低，这可能解释了在初次抗NP反应中λ链占主导地位的现象。

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Detection and isolation of anti-hapten antibody-secreting cells by cellular affinity matrix technology.

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Role of conserved amino acid residues in the complementarity determining regions on hapten-antibody interaction of anti-(4-hydroxy-3-nitrophenyl) acetyl antibodies.保守氨基酸残基在抗（4-羟基-3-硝基苯基）乙酰抗体的半抗原-抗体相互作用的互补决定区中的作用。

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Differences in antibody repertoires for (4-hydroxy-3-nitrophenyl)acetyl (NP) in splenic vs immature bone marrow precursor cells.脾脏与未成熟骨髓前体细胞中针对（4-羟基-3-硝基苯基）乙酰基（NP）的抗体库差异。

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Crystallization and preliminary X-ray diffraction studies of an anti-4-hydroxy-3-nitrophenylacetic acid monoclonal antibody Fab fragment complexed with immunizing and heteroclitic haptens.与免疫原性半抗原和交叉反应性半抗原复合的抗4-羟基-3-硝基苯乙酸单克隆抗体Fab片段的结晶及初步X射线衍射研究

J Mol Biol. 1989 Sep 20;209(2):319-21. doi: 10.1016/0022-2836(89)90280-5.

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