甲状腺功能减退症中的可逆性IgA缺乏症。
Reversible IgA deficiency in hypothyroidism.
作者信息
Eriksson S
出版信息
Postgrad Med J. 1981 Nov;57(673):714-6. doi: 10.1136/pgmj.57.673.714.
Abstract
A 50-year-old woman developed pronounced IgA-deficiency and hypothyroidism after I treatment for Graves' disease. The deficiency state was associated with a severe sinobronchial syndrome. Treatment with L-thyroxine resulted in a normal IgA concentration and a dramatic clinical improvement. Of the various possible underlying mechanisms, impaired synthesis of IgA light and heavy light chains seemed most probable. Impaired production of J-chain was excluded.
摘要
一名50岁女性在接受格雷夫斯病的碘治疗后出现明显的IgA缺乏和甲状腺功能减退。这种缺乏状态与严重的鼻窦支气管综合征相关。左甲状腺素治疗使IgA浓度恢复正常，并带来显著的临床改善。在各种可能的潜在机制中，IgA轻链和重链合成受损似乎最有可能。已排除J链产生受损的情况。
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