Jezernik M
Acta Chir Iugosl. 1981;28(2):235-8.
The paper presents the incidence of infection observed in 108 patients subjected to ventriculoatrial shunting at the Department of Neurosurgery, University Medical Centre of Ljubljana. Infection was established in 17 (15.8%) Pudenz's shunts. It is most likely to develop within the first year following the shunt implantation. The most common clinical symptom associated with the shunt infection is an obscure, moderately elevated body temperature (about 38 degrees C) of several weeks duration. The infected shunt should be removed without delay and replaced by external ventricular drainage with an uniflow valve and an added piece for the intraventricular administration of the antibiotic. Before the results of the cerebrospinal fluid and drainage system cultures are known, the Methicillin therapy of 200 mg/kg daily should be initiated and followed by the adequate antibiotic therapy consistent with the culture findings. Should the antibiotic therapy administered by this route fail to control the infection, additional intraventricular instillation is to be instituted.
本文介绍了卢布尔雅那大学医学中心神经外科对108例接受脑室-心房分流术患者的感染发生率。在17例(15.8%)Pudenz分流术中发现了感染。感染最有可能在分流植入后的第一年内发生。与分流感染相关的最常见临床症状是持续数周的不明原因、中度体温升高(约38摄氏度)。应立即移除感染的分流器,并用带单向阀的外部脑室引流管及用于脑室内给予抗生素的附加部件进行替换。在脑脊液和引流系统培养结果出来之前,应开始每日200mg/kg的甲氧西林治疗,随后根据培养结果进行适当的抗生素治疗。如果通过这种途径给予的抗生素治疗未能控制感染,则应进行额外的脑室内滴注。