Abbaticchio G, Giorgino R, Gentile F M, Cassano A, Gattuccio F, Orlando G, Jannì A
Acta Eur Fertil. 1981 Sep;12(3):255-60.
On the basis of the results in vitro, it seems that the testicle does not respond to the action of the thyroid hormones. The study of the relationship between the blood concentrations of these hormones and the reproductive function of the organ is being made by the Authors as a means of verifying this in vivo. The total blood concentrations of T4, (triioothyronine), and the index of free Thyroxine (IT4L) were therefore evaluated both in normal and infertile subjects. The concentrations of T4 showed a correlation both with the sperm count (r = 0.43, p = less than 0.02), and with the percentage of motile spermatozoa, (r = 0.48, p = less than 0.01). This type of correlation is not found, however, either for the T3 or for the IT4L. These data indicate that the function of the thyroid gland is linked to that of the hypothalamo-hypophyseotesticular axis. It would appear that the peripheric metabolism of the circulating hormones is not involved.
根据体外实验结果，睾丸似乎对甲状腺激素的作用没有反应。作者正在研究这些激素的血药浓度与该器官生殖功能之间的关系，以此作为在体内验证这一现象的一种手段。因此，对正常受试者和不育受试者的总血T4（三碘甲状腺原氨酸）浓度以及游离甲状腺素指数（IT4L）进行了评估。T4浓度与精子计数（r = 0.43，p < 0.02）以及活动精子百分比（r = 0.48，p < 0.01）均呈相关性。然而，无论是T3还是IT4L，均未发现这种相关性。这些数据表明，甲状腺功能与下丘脑 - 垂体 - 睾丸轴的功能相关。似乎循环激素的外周代谢并不涉及其中。
