Klimek A, owczarczyk I, Głuszcz-Zielińska A
Neurol Neurochir Pol. 1981 Sep-Dec;15(5-6):569-73.
In 18 men with Horton's headaches the levels of the following hormones were determined in the serum: TSH, T3 and T4. The determinations were performed during disease relapse and before starting treatment. The control group included 18 blood donors. In the control group the mean TSH level was 3.97 +/- 0.88 microunits/ml, T4 level was 109.06 +/- 26.88 nmol/l, and T3 1.48 +/- 0.14 nmol/l. In the group of patients the mean values were: 2.58 +/- 2.09 microunits/ml, 97.62 +/- 21.81 nmol/l, 1.07 +/- 0.21 nmol/l respectively. The analysis of the results showed statistically significant differences in the concentrations of T3 between the compared groups. In the light of these results the authors believe that there is not sufficient support of the hypothesis on a hypothalamic pathogenesis of the disease. The causes of reduced T3 concentration in these patients are discussed.
在18例患有霍顿氏头痛的男性患者中，测定了血清中以下激素的水平：促甲状腺激素（TSH）、三碘甲状腺原氨酸（T3）和甲状腺素（T4）。这些测定在疾病复发期间和开始治疗前进行。对照组包括18名献血者。对照组中促甲状腺激素的平均水平为3.97±0.88微单位/毫升，甲状腺素水平为109.06±26.88纳摩尔/升，三碘甲状腺原氨酸为1.48±0.14纳摩尔/升。在患者组中，平均值分别为：2.58±2.09微单位/毫升、97.62±21.81纳摩尔/升、1.07±0.21纳摩尔/升。结果分析显示，比较组之间三碘甲状腺原氨酸浓度存在统计学上的显著差异。根据这些结果，作者认为，关于该疾病下丘脑发病机制的假说没有得到充分支持。文中讨论了这些患者三碘甲状腺原氨酸浓度降低的原因。
