大鼠体内 N-烷基苯丙胺的代谢——N-烷基链长度对芳环氧化的影响。
In vivo metabolism of N-alkylamphetamines in the rat--the effect of N-alkyl chain length on oxidation of the aromatic ring.
作者信息
Coutts R T, Dawson G W, Jones G R
出版信息
Res Commun Chem Pathol Pharmacol. 1978 Dec;22(3):589-92.
PMID:734236
Abstract
In vivo metabolism of N-alkylated amphetamines in the rat produced 4-hydroxy- and 4-hydroxy-3-methoxy-metabolites. The relative quantities of the phenolicmetabolites formed were dependent upon the length of the N-alkyl substituent.
摘要
大鼠体内 N-烷基化苯丙胺的代谢产生了 4-羟基和 4-羟基-3-甲氧基代谢物。形成的酚类代谢物的相对量取决于 N-烷基取代基的长度。
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