Freire-Maia D V, Freire-Maia A
Trop Geogr Med. 1981 Dec;33(4):387-92.
A sample of 2688 individuals, about half of them showing endemic goitre, has been studied in a hyper-endemic area of the state of Mato Grosso, Brazil. The codified data were processed in computers. Analyses through contrasts among multinominal proportions showed Negroes and Mulattoes with higher frequencies of goitre than Whites, thus agreeing with results from the literature. A number of multiple regression models, including 21 independent variables, showed no evidence of any intrinsic racial effect on the occurrence of goitre. The authors conclude that the higher prevalence of goitre among Malattoes and Negroes probably reflects the influence of their poorer socio-economic conditions. Although genetic factors are generally assumed to play some role in the development of goitre, it is to environmental causes that the most important role is ascribed.
在巴西马托格罗索州的一个甲状腺肿高发地区，对2688名个体进行了抽样研究，其中约一半人患有地方性甲状腺肿。编码数据在计算机中进行处理。通过多项比例对比分析发现，黑人和混血儿的甲状腺肿发病率高于白人，这与文献中的结果一致。一些包含21个自变量的多元回归模型没有显示出任何种族内在因素对甲状腺肿发病有影响的证据。作者得出结论，混血儿和黑人中甲状腺肿的较高患病率可能反映了他们较差的社会经济状况的影响。虽然一般认为遗传因素在甲状腺肿的发展中起一定作用，但最重要的作用归因于环境因素。
