Unusual sites of lung tumor metastases in B6C3F1 mice and F344 rats.

Three male control B6C3F1 mice, one male and one female F344 rat were found to have lung tumours with unusual sites of distant metastases. The neoplasms spread to the regional lymph nodes, left heart, kidney, prostate and testes. One mouse showed metastases to the brain. Each had a metastasizing lung tumor in the medulla and cortex of the right adrenal gland and one neoplasm had spread to the heart, pancreas and kidney.