Mantanus H, Timsit-Berthier M, Gerono A, von Frenckell R
Biol Psychol. 1981 Dec;13:227-37. doi: 10.1016/0301-0511(81)90038-7.
Contingent negative variation (CNV), reaction time (RT), and EEG power spectrum were measured in a group of 27 neurotics and 26 controls subjects, male and female, aged 18 to 38. CNV was recorded with a 1 sec interstimulus interval and averaged over 48 trials. Two spectral analyses of the EEG were performed, the first during the 1 sec period preceding S1 (spontaneous EEG), the second during the S1-S2 interval (activated EEG). For each group of subjects, we calculated the correlations between four measures of CNV amplitude, RT duration, and the relative powers of the delta, theta, alpha and beta activities during spontaneous and activated EEG. In neurotic subjects there was an absence of correlation between the pre- and post-imperative segments of the CNV, and between early CNV amplitude and per cent alpha power. Both groups shared in common strong correlations relating CNV amplitude and RT length, on the one hand, and the different components of the EEG spectrum, on the other hand, Principal component analysis applied to the pooled data revealed different factors for CNV and EEG parameters, suggesting independence of the neurophysiological mechanisms implied in the two phenomena.
对27名神经症患者和26名对照者（年龄在18至38岁之间，有男有女）进行了关联性负变（CNV）、反应时间（RT）和脑电图功率谱测量。CNV采用1秒的刺激间隔进行记录，并在48次试验中求平均值。对脑电图进行了两次频谱分析，第一次在S1前1秒期间（自发脑电图），第二次在S1 - S2间隔期间（激活脑电图）。对于每组受试者，我们计算了CNV幅度的四种测量值、RT持续时间以及自发和激活脑电图期间δ、θ、α和β活动的相对功率之间的相关性。在神经症患者中，CNV的指令前和指令后段之间以及早期CNV幅度与α功率百分比之间不存在相关性。两组都存在共同的强相关性，一方面是CNV幅度与RT长度之间的相关性，另一方面是脑电图频谱的不同成分之间的相关性。对合并数据进行主成分分析揭示了CNV和脑电图参数的不同因素，表明这两种现象所涉及的神经生理机制相互独立。
