Vajola S F, Chiavarelli V, Milazzotto F
G Ital Cardiol. 1981;11(11):1743-9.
Treatment of recurrent ventricular tachycardia (RVT) is still difficult, as far as choice of antiarrhythmic agents, dosage, associations and statement of their effectiveness are concerned; the Authors report their experience on twelve cases of RVT. The diagnosis of ventricular tachycardia was confirmed by esophageal electrograms in four cases and by intracardiac recordings in two cases. Patients were controlled by clinical observation, continuous electrocardiographic monitoring and several recordings. Ambulatory electrocardiographic monitoring was carried out in ten patients. Two patients left the hospital spontaneously; therapy was found to be effective in the remainder. Four patients were treated with quinidine plus betablockers, for cases with quinidine plus amiodarone. The results of long-term follow-up suggest that combined pharmacological therapy with drugs of different classes may be successful in preventing recurrences of ventricular tachycardia. The Authors think that careful choices of adequate therapeutic programs and rigid criteria for the evaluation of results should be planned in apparent refractory RVT, before referring to invasive procedures.
就抗心律失常药物的选择、剂量、联合用药及其有效性而言，复发性室性心动过速（RVT）的治疗仍然困难重重；作者报告了他们对12例RVT患者的治疗经验。4例患者通过食管心电图确诊室性心动过速，2例通过心内记录确诊。通过临床观察、连续心电图监测和多次记录对患者进行监测。10例患者进行了动态心电图监测。2例患者自动出院；其余患者的治疗有效。4例患者接受了奎尼丁加β受体阻滞剂治疗，另有病例接受奎尼丁加胺碘酮治疗。长期随访结果表明，不同类别的药物联合药物治疗可能成功预防室性心动过速复发。作者认为，在考虑采用侵入性治疗之前，对于明显难治性RVT，应精心选择适当的治疗方案并制定严格的疗效评估标准。
