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传出副本与伴随放电:对思维及其障碍的影响

Efference copy and corollary discharge: implications for thinking and its disorders.

作者信息

Feinberg I

出版信息

Schizophr Bull. 1978;4(4):636-40. doi: 10.1093/schbul/4.4.636.

DOI:10.1093/schbul/4.4.636
PMID:734369
Abstract

Many motor commands in the nervous system are associated with corollary discharges which alter the excitability in both sensory and motor systems. These discharges may assist in the distinction between self-generated and externally produced movements; they also allow (or represent) monitoring of the motor commands before the effector response has occurred. Here, I hypothesize that this mechanism of control and integration is also present in thinking, which as Hughlings Jackson pointed out, may be considered the highest and most complex form of motor activity. I speculate that if corollary discharges are normally part of the motor mechanisms of thought, their derangement could produce many of the symptoms of schizophrenia.

摘要

神经系统中的许多运动指令都与伴随放电相关,这些放电会改变感觉和运动系统的兴奋性。这些放电可能有助于区分自我产生的运动和外部产生的运动;它们还允许(或代表)在效应器反应发生之前对运动指令进行监测。在此,我假设这种控制和整合机制在思维中也存在,正如休林斯·杰克逊所指出的,思维可能被认为是运动活动的最高和最复杂形式。我推测,如果伴随放电通常是思维运动机制的一部分,那么它们的紊乱可能会产生许多精神分裂症的症状。

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