Belloli G P, Campobasso P, Girardi G F, Termini C
Pediatr Med Chir. 1981 Nov-Dec;3(6):481-5.
Nine children with total anal incontinence after surgery for anorectal agenesis were successfully operated on by free autogenous muscle transplantation. Skeletal muscles were first denervated and 3 weeks later transplanted to the anal region as a U--sling around the rectum, imitating the normal position and function of the puborectalis muscle. The grafts were placed in contact with the normal muscles of the region to make reinnervation possible. Eight children were completely evaluated after operation. Two years after surgical procedure six children were "continent" and only two were still incontinent, but improved. In these cases the indication for muscle transplantation was not quite correct. The return of the function of the muscle grafts completely changed the lives of these children. The results of this new surgical procedure are encouraging and invite further trials.
9例肛门直肠闭锁术后完全性肛门失禁的患儿通过自体肌肉移植手术获得成功。首先对骨骼肌进行去神经支配,3周后将其作为围绕直肠的U形吊带移植到肛门区域,模仿耻骨直肠肌的正常位置和功能。将移植物放置在与该区域正常肌肉接触的位置,以使再神经支配成为可能。8例患儿术后得到了全面评估。手术两年后,6例患儿实现了“控便”,只有2例仍有失禁,但情况有所改善。在这些病例中,肌肉移植的指征并不完全正确。肌肉移植物功能的恢复彻底改变了这些患儿的生活。这种新手术方法的结果令人鼓舞,值得进一步试验。