Spehr W, Sartorius H, Berglund K, Hjorth B, Kablitz C, Plog U, Wiedemann P H, Zapf K
Electroencephalogr Clin Neurophysiol. 1977 Dec;43(6):787-97. doi: 10.1016/0013-4694(77)90001-3.
Computerized EEG was performed in 20 patients with renal failure before and after haemodialysis (HD), applying spectral analysis and Hjorth's EEG descriptors in EEG quantification, correlation and factor analysis as statistical procedures to analyse the connections of EEG, blood variables and psychological performance. The main results were: (1) Moderate uraemic encephalopathy -- according to Kiley's (1971) standards -- was present in most of our patients, before and after HD. (2) Before HD, EEG slowing was most strongly connected with the creatinine level and EEG acceleration with hyperkalaemia, which in most cases accompanied a high urea level. (3) Significant EEG changes after HD were: decrease of percentage delta activity, increase of Hjorth's 'mobility', decrease of Hjorth's 'complexity'. (4) The theta/alpha ratio (Matousek 1968) was significantly correlated with the patient's general clinical state after HD. (5) Visual discrimination, memory and maximal tapping speed improved significantly after HD. Only Hjorth's EEG parameters were correlated with test performance in that patients with low voltage and fast EEGs did worse in visual discrimination.
对20例肾衰竭患者在血液透析(HD)前后进行了计算机化脑电图检查,应用频谱分析和Hjorth脑电图描述符进行脑电图量化、相关性和因子分析,作为分析脑电图、血液变量和心理表现之间联系的统计程序。主要结果如下:(1)根据Kiley(1971年)的标准,大多数患者在HD前后均存在中度尿毒症脑病。(2)HD前,脑电图减慢与肌酐水平最密切相关,脑电图加速与高钾血症相关,在大多数情况下,高钾血症伴有高尿素水平。(3)HD后脑电图的显著变化为:δ活动百分比降低、Hjorth“移动性”增加、Hjorth“复杂性”降低。(4)θ/α比值(Matousek,1968年)与HD后患者的一般临床状态显著相关。(5)HD后视觉辨别、记忆力和最大敲击速度显著改善。只有Hjorth脑电图参数与测试表现相关,即低电压和快速脑电图患者的视觉辨别能力较差。