Ghezzi E, Tassi G C
Boll Ist Sieroter Milan. 1981;60(6):538-46.
The Authors report the results obtained with the histamine radioenzymatic test in the evaluation of the histamine content of granulocytes of 91 subjects, suffering from urticaria and urticaria-angioedema syndrome. The laboratory investigation was also integrated, according to the clinical implications, by other in vitro tests such as: kallikrein, RAST, PRIST, secretory IgA, precipitins assays. In urticaria-angioedema syndrome the quantitative and functional evaluation of C1-esterase inhibitor was also performed, to exclude the heredity of these pathologic forms. Basing on the results obtained, the authors expect that the granulocyte histamine radioenzymatic assay is highly reliable from the diagnostic viewpoint in the urticaria and angioedema forms.
作者报告了用组胺放射酶法检测91例患有荨麻疹和荨麻疹 - 血管性水肿综合征患者的粒细胞组胺含量所获得的结果。根据临床意义，实验室检查还通过其他体外试验进行补充，如：激肽释放酶、放射变应原吸附试验（RAST）、被动放射免疫吸附试验（PRIST）、分泌型免疫球蛋白A、沉淀素测定。对于荨麻疹 - 血管性水肿综合征，还进行了C1酯酶抑制剂的定量和功能评估，以排除这些病理形式的遗传性。基于所获得的结果，作者预计粒细胞组胺放射酶测定法从诊断角度来看在荨麻疹和血管性水肿形式中具有高度可靠性。
