Roncali L, Bertossi M, Ribatti D
Bull Assoc Anat (Nancy). 1981 Dec;65(191):489-97.
The modifications of the extent and ultrastructure of the perivascular spaces during the development of blood vessel networks in the pars distalis of the adenohypophysis have been analyzed in normally developing chick embryos, from the 7th incubation day to hatching. The quantitative evaluation of the changes undergone by the perivascular spaces, carried out on semithin sections, showed that their extent gradually decreases and that this reduction is paralleled by an increment of the extent of the capillary bed. The ultrastructural study of the hypophyseal sinusoids allowed a precise determination of the size and the minute morphology of these spaces, which attain their definitive characters only during the late incubation stages, when the endothelial basement lamina forms.
在正常发育的鸡胚中，从孵化第7天到孵化结束，分析了腺垂体远侧部血管网络发育过程中血管周围间隙的范围和超微结构变化。在半薄切片上对血管周围间隙所经历的变化进行定量评估，结果显示其范围逐渐减小，且这种减小与毛细血管床范围的增加同时出现。对垂体血窦的超微结构研究能够精确确定这些间隙的大小和细微形态，这些间隙仅在孵化后期内皮基底膜形成时才具有其最终特征。
