Cohen S N
Pediatr Pharmacol (New York). 1980;1(1):25-9.
Clinical pharmacology in pediatrics has been impeded for a number of years by ethical and legal issues which have been impossible to resolve by individual investigators and by society at large. The ethical issues involved in such research, in children, have been defined more clearly in the recent past and investigators now have a number of guidelines to follow in constructing and carrying out their studies. The ultimate legal status of clinical pharmacology studies in children is still to be defined, but sensitive investigators who work with competent institutional review boards should be able to advance our knowledge through clinical studies in children without major liability.
多年来，儿科临床药理学一直受到伦理和法律问题的阻碍，这些问题是个别研究人员和整个社会都无法解决的。近年来，此类涉及儿童的研究中的伦理问题已得到更明确的界定，研究人员现在在构建和开展研究时有多项指导方针可循。儿童临床药理学研究的最终法律地位仍有待确定，但与有资质的机构审查委员会合作的审慎研究人员应该能够通过儿童临床研究增进我们的知识，而不会承担重大责任。
