Baron J, Sobieszczyk S
Zentralbl Gynakol. 1981;103(16):929-34.
Clinical and hormonal examinations were applied to 30 patients with secondary amenorrhoea, following loss of weight, and to another 24 women with nervous anorexia. Low age, secondary amenorrhoea, and unambiguous loss of weight were typical of all patients. In patients with hypothalamic syndrome, following loss of weight, both psychic condition and appetite were found to be normal, whereas psychogenic aversion against appetite was recordable from patients with nervous anorexia. Oestrogens were slightly reduced in patients with hypothalamic syndrome, following loss of weight, but they were strongly down in the presence of nervous anorexia. Gonadotrophin values were normal or low in patients with hypothalamic syndrome, following loss of weight, but they were clearly reduced in the second group. The LH-RH test usually was normal in patients with hypothalamic syndrome, following loss of weight, but it was pathological in almost all cases of nervous anorexia, depending on the amount of weight loss.
对30例体重减轻后出现继发性闭经的患者以及另外24例神经性厌食症女性进行了临床和激素检查。所有患者均具有年龄小、继发性闭经和明确的体重减轻特点。体重减轻后出现下丘脑综合征的患者,其精神状态和食欲均正常,而神经性厌食症患者存在对食欲的心理厌恶。体重减轻后出现下丘脑综合征的患者雌激素略有降低,但神经性厌食症患者雌激素则显著降低。体重减轻后出现下丘脑综合征的患者促性腺激素值正常或偏低,但第二组患者促性腺激素值明显降低。体重减轻后出现下丘脑综合征的患者LH-RH试验通常正常,但几乎所有神经性厌食症患者的该试验均呈病理性,具体取决于体重减轻的程度。