Ugriumov M V
Tsitologiia. 1978 Nov;20(11):1243-8.
The penetration of horseradish peroxidase and ferritin into the neurosecretory axones in the rat's posterior pituitary has been studied with the electron microscope. Markers were revealed in neurosecretory granules, in empty vesicles of the same size, in neurotubules, in lamellar bodies and in the axoplasm. Markers were taken up from the extracellular space by micropinocytotic "synaptic" vesicles and probably by larger empty vesicles. It is supposed that the contents of these vesicles penetrate into the granules to take part in their maturation. Besides, the contents of synaptic vesicles probably penetrate into neurotubules and are retrogradally transported to perikaryons of neusecretory cells. Ferritin is taken up from axoplasm by lamellar bodies that possess lysosomal activity.
用电子显微镜研究了辣根过氧化物酶和铁蛋白进入大鼠垂体后叶神经分泌轴突的情况。在神经分泌颗粒、大小相同的空泡、神经微管、板层小体和轴质中发现了标记物。标记物通过微胞饮“突触”小泡以及可能通过较大的空泡从细胞外空间摄取。据推测，这些小泡的内容物渗透到颗粒中以参与其成熟过程。此外，突触小泡的内容物可能渗透到神经微管中，并逆行运输到神经分泌细胞的核周体。铁蛋白被具有溶酶体活性的板层小体从轴质中摄取。
