Miceli G, Caltagirone C, Gainotti G, Masullo C, Silveri M C, Villa G
Acta Neurol Scand. 1981 Nov;64(5):370-82. doi: 10.1111/j.1600-0404.1981.tb04416.x.
The influence of sex, age, educational level and pathologic lesion on incidence, severity and clinical form of aphasia was investigated in 390 right-handed, left brain-damaged patients. Sex and educational level were not related to any parameter. Etiology of lesion and age were related to both incidence and type of aphasia. Incidence of aphasia increased with age and was higher in patients with cerebrovascular accidents than in subjects with other types of brain lesions. Non-fluent forms of aphasia were more frequent in young patients suffering from acute cerebrovascular accidents, whereas anomia prevailed in neoplastic subjects and Wernicke's aphasia increased regularly in frequency with age. Some tentative explanations of these findings are discussed.
对390例右利手、左脑损伤患者的性别、年龄、教育程度和病理损害对失语症的发病率、严重程度和临床类型的影响进行了研究。性别和教育程度与任何参数均无关联。病变病因和年龄与失语症的发病率和类型均相关。失语症的发病率随年龄增长而增加,脑血管意外患者的发病率高于其他类型脑损伤的患者。非流畅型失语症在患有急性脑血管意外的年轻患者中更为常见,而命名性失语在肿瘤患者中占主导,韦尼克失语症的发病率随年龄有规律地增加。文中讨论了对这些发现的一些初步解释。