Kurup V P, Sheth N K
Comp Immunol Microbiol Infect Dis. 1981;4(2):161-74. doi: 10.1016/0147-9571(81)90002-3.
Controls, as well as cortisone-treated rabbits, were challenged with Aspergillus fumigatus spores intratracheally. Animals were sacrificed 3, 7, 14 and 28 days after inoculation and their organs cultured and studied histologically. Lesions were produced in both groups, although the cortisone-treated group showed greater pathology and the lesions persisted for a longer period of time than the control groups. Histologically, the pulmonary lesions showed granulomatous pulmonary aspergillosis and suppurative necrotizing pneumonic infiltrates.
对照组以及接受可的松治疗的兔子通过气管内注射烟曲霉菌孢子进行激发。在接种后3天、7天、14天和28天处死动物，并对其器官进行培养和组织学研究。两组均出现了病变，尽管接受可的松治疗的组病变更为严重，且病变持续的时间比对照组更长。组织学上，肺部病变表现为肉芽肿性肺曲霉病和化脓性坏死性肺炎浸润。
