Bach A, Boulangé A, Schirardin H, de Gasquet P
Reprod Nutr Dev (1980). 1981;21(6A):929-36. doi: 10.1051/rnd:19810705.
At 3 weeks of age, Zucker rats could not be classified as normal or obese according to body or liver weight. On the other hand, determination of subcutaneous adipose tissue weight per 100 grams of body weight permitted both phenotypes to be distinguished, provided that the growth variations particular to each litter were taken into account. Rats whose future obesity is predictable using this method, have significantly elevated serum levels of triacylglycerols, total cholesterol and phospholipids. However, further analysis of these values indicated that in fact there were two subgroups of both obese and non-obese rats, i.e., those which had elevated serum lipid levels and those which did not.
在3周龄时，根据体重或肝脏重量，无法将 Zucker 大鼠分类为正常或肥胖。另一方面，每100克体重的皮下脂肪组织重量的测定能够区分两种表型，前提是考虑到每窝特有的生长差异。使用这种方法可预测未来肥胖的大鼠，其血清甘油三酯、总胆固醇和磷脂水平显著升高。然而，对这些值的进一步分析表明，实际上肥胖和非肥胖大鼠都有两个亚组，即血清脂质水平升高的大鼠和未升高的大鼠。
