Braunstein P W, DeGirolami U
Acta Neuropathol. 1981;55(3):167-72. doi: 10.1007/BF00691314.
The steroids triamcinolone, dexamethasone, beta-methasone, and cortisone were administered i.p. to adult rats for 14-63 days. The extensor digitorum longus (EDL, white muscle) and soleus (SOL, red muscle) muscles were examined histologically and histochemically. Triamcinolone was the most potent lesion-producing drug. Selective involvement of muscles, and of the fiber types within them was observed: Necrotic changes were seen only in the type 1 fibers of the SOL; atrophic fibers were observed in the type 2 fibers of both the SOL and the EDL.
将曲安奈德、地塞米松、倍他米松和可的松等类固醇腹腔注射给成年大鼠，持续14至63天。对趾长伸肌（EDL，白色肌肉）和比目鱼肌（SOL，红色肌肉）进行组织学和组织化学检查。曲安奈德是最易产生损伤的药物。观察到肌肉及其内部纤维类型的选择性受累情况：仅在比目鱼肌的1型纤维中出现坏死变化；在比目鱼肌和趾长伸肌的2型纤维中均观察到萎缩纤维。
