Chen E H, Black J
J Biomed Mater Res. 1980 Sep;14(5):567-86. doi: 10.1002/jbm.820140504.
Repair or replacement of the damaged anterior cruciate ligament (ACL) is a significant clinical problem. A design utilizing ultrahigh-molecular-weight polyethylene (UHMWPE) was developed and marketed by an orthopaedic device manufacturer. Mechanical failure rates of greater than 10%/year postoperatively raised the issue of the adequacy of UHMWPE in that design. A study has been made to estimate the forces in the human anterior cruciate ligament for young, middle age, and older patients and to thus derive the minimum materials requirements for a now withdrawn prosthetic anterior cruciate ligament (PACL) design. It is concluded that UHMWPE does not possess adequate yield, creep, or fatigue properties to meet the design. Furthermore, consideration of the varying requirements on the PACL, due to differences in age and activity levels of patients, suggest that a band-type design offers a better possibility of achieving adequate materials performance in the ACL prosthetic replacement.
修复或替换受损的前交叉韧带（ACL）是一个重大的临床问题。一种使用超高分子量聚乙烯（UHMWPE）的设计由一家骨科器械制造商研发并推向市场。术后每年机械故障率超过10%，这引发了该设计中UHMWPE是否足够的问题。已经进行了一项研究，以估计年轻、中年和老年患者的人体前交叉韧带中的力，从而得出现已停用的人工前交叉韧带（PACL）设计的最低材料要求。得出的结论是，UHMWPE不具备足够的屈服、蠕变或疲劳性能来满足该设计。此外，考虑到患者年龄和活动水平的差异对PACL的不同要求，表明带状设计在ACL假体置换中更有可能实现足够的材料性能。
