Shaeffer J, El-Mahdi A M, Carr K L
Cancer Detect Prev. 1981;4(1-4):571-8.
Our laboratory has begun to evaluate the cancer detection capabilities of a microwave thermographic unit that employs a 4.7 GHz radiometer. The technique is passive and noninvasive. The temperature sensitivity of the unit is less than 0.1 degrees C. Malignant tumors are often about 1 degree C warmer than normal tissues. Microwave radiometry can provide information related to subsurface temperatures, whereas infrared thermography is limited to surface temperatures. Positive results were obtained in four of six biopsy-proved primary carcinomas of the breast, in four of four patients with lymphoma, and in nine of ten women with recurrent breast cancer. Negative results were obtained in patients with deeply seated tumors such as in lung, liver, esophagus, femur, and humerus. Microwave thermography is a promising new method of noninvasive cancer detection, and the choice of a 4.7 GHz frequency may represent an improvement over units operated at other frequencies.
我们实验室已开始评估一台采用4.7吉赫兹辐射计的微波热成像设备检测癌症的能力。该技术是被动且无创的。该设备的温度灵敏度小于0.1摄氏度。恶性肿瘤通常比正常组织温度高约1摄氏度。微波辐射测量法可提供与皮下温度相关的信息,而红外热成像仅限于表面温度。在经活检证实的6例原发性乳腺癌中有4例、4例淋巴瘤患者中的4例以及10例复发性乳腺癌女性中的9例获得了阳性结果。在患有深部肿瘤(如肺癌、肝癌、食管癌、股骨和肱骨肿瘤)的患者中获得了阴性结果。微波热成像是一种很有前景的无创癌症检测新方法,选择4.7吉赫兹频率可能比其他频率运行的设备有所改进。