Goodman R A, Hinman A R, Nolan T F, Brandling-Bennett A D
Am Fam Physician. 1980 Jan;21(1):101-5.
The hemagglutinin and neuraminidase surface antigens of the influenza virus periodically undergo major or minor structural changes. These influence epidemiologic patterns and the composition of vaccine. Annual vaccination is recommended for individuals at increased risk of complications from lower respiratory tract infections. Vaccine for 1979-80 contains antigens representative of three viruses and is closely related to the vaccine of 1978-79. Amantadine is approved for prophylaxis and treatment.
流感病毒的血凝素和神经氨酸酶表面抗原会定期发生重大或微小的结构变化。这些变化会影响流行病学模式和疫苗的成分。建议每年对下呼吸道感染并发症风险增加的个体进行疫苗接种。1979 - 1980年的疫苗含有三种病毒的代表性抗原，且与1978 - 1979年的疫苗密切相关。金刚烷胺已被批准用于预防和治疗。
