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肾血管性高血压:经皮腔内扩张治疗

Renovascular hypertension: treatment by percutaneous transluminal dilatation.

作者信息

Kuhlmann U, Vetter W, Furrer J, Lütolf U, Siegenthaler W, Grüntzig A

出版信息

Ann Intern Med. 1980 Jan;92(1):1-6. doi: 10.7326/0003-4819-92-1-1.

Abstract

Eight patients with unilateral renovascular hypertension underwent percutaneous transluminal dilatation. In seven, renal-artery stenoses were caused by atherosclerotic lesions and in one, by fibromuscular hyperplasia. After a 6-month follow-up period, three patients were cured of hypertension anf four showed improvement. Only one patient failed to respond: Failure was caused by an occluded left renal artery 3 months after the procedure. Renal angiographic studies were repeated in six patients after 6 months of follow-up and showed patent vessels in five and reoccurrence of a slight renal-artery stenosis in one. In one patient angiographic control studies done after 3 months showed an occluded renal artery. In five patients mean pressure gradient across the renal-artery stenoses was 89 +/- 22.8 mm Hg before percutaneous transluminal dilatation and 16.4 +/- 18.5 mm Hg after being controlled for 6 months. Our results indicate that percutaneous transluminal dilatation may be valuable in the treatment of renovascular hypertension.

摘要

8例单侧肾血管性高血压患者接受了经皮腔内扩张术。其中7例肾动脉狭窄由动脉粥样硬化病变引起,1例由纤维肌增生引起。经过6个月的随访期,3例患者高血压治愈,4例病情改善。仅1例患者无效:无效原因是术后3个月左肾动脉闭塞。6例患者在随访6个月后重复进行了肾血管造影研究,结果显示5例血管通畅,1例再次出现轻度肾动脉狭窄。1例患者在术后3个月进行的血管造影对照研究显示肾动脉闭塞。5例患者经皮腔内扩张术前肾动脉狭窄处的平均压力梯度为89±22.8 mmHg,控制6个月后为16.4±18.5 mmHg。我们的结果表明,经皮腔内扩张术在肾血管性高血压的治疗中可能具有重要价值。

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