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拟胆碱药与记忆。氯化胆碱的作用。

Cholinomimetics and memory. The effect of choline chloride.

作者信息

Davis K L, Mohs R C, Tinklenberg J R, Hollister L E, Pfefferbaum A, Kopell B S

出版信息

Arch Neurol. 1980 Jan;37(1):49-52. doi: 10.1001/archneur.1980.00500500079013.

Abstract

Young normal subjects received 16 g of choline chloride in a double-blind A-B-A design. Short- and long-term memory function was evaluated. Comparison of group means indicated that choline chloride did not significantly affect short-term memory or long-term memory. However, individual subjects may have had some aspects of long-term memory affected by choline chloride treatments. The results suggest that the effect of lower doses of choline on long-term memory should be evaluated.

摘要

年轻的正常受试者在双盲A - B - A设计中接受了16克氯化胆碱。对短期和长期记忆功能进行了评估。组均值比较表明,氯化胆碱对短期记忆或长期记忆没有显著影响。然而,个别受试者的长期记忆的某些方面可能受到了氯化胆碱治疗的影响。结果表明,应评估较低剂量胆碱对长期记忆的影响。

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