特应性皮炎中的人类白细胞抗原。一项家族研究。

HLA antigens in atopic dermatitis. A family study.

作者信息

Larsen F S, Grunnet N, Vase P

出版信息

Dermatologica. 1980;160(1):17-20. doi: 10.1159/000250461.

Abstract

The HLA antigens in a family with atopic dermatitis were studied. All family members with atopic dermatitis had haplotype A2, Bw35, Cw4. It has been recently demonstrated that HLA type Bw35 is found with an increased frequency in atopic dermatitis. There appears to be an inconsistent and weak correlation between atopic dermatitis and HLA-A, HLA-B and HLA-C loci.

摘要

对一个患有特应性皮炎的家庭中的人类白细胞抗原（HLA）进行了研究。所有患有特应性皮炎的家庭成员都具有单倍型A2、Bw35、Cw4。最近已经证明，在特应性皮炎患者中，Bw35型HLA的出现频率有所增加。特应性皮炎与HLA - A、HLA - B和HLA - C基因座之间似乎存在不一致且微弱的相关性。