Fujishima M, Omae T
Gerontology. 1980;26(2):104-7. doi: 10.1159/000212402.
Brain blood flow and mean transit time were measured in 41 normotensive control subjects aged from 21 to 76 years by using the intravenous 131I-RISA external counting method. The results showed a significant prolongation of mean transit time and a tendency to increase in brain blood volume relating to advancing age but no change in the blood flow. This indicates that prolonged transit time in the aged is probably due to the increased brain blood volume.
采用静脉注射¹³¹I - RISA体外计数法,对41名年龄在21岁至76岁之间的血压正常的对照受试者进行脑血流量和平均通过时间的测量。结果显示,平均通过时间显著延长,脑血容量有随年龄增长而增加的趋势,但血流量无变化。这表明老年人通过时间延长可能是由于脑血容量增加所致。