阿司匹林对体外补体系统的作用。
Effect of aspirin on the complement system in vitro.
作者信息
Hänsch G M, Voigtländer V, Rother U
出版信息
Int Arch Allergy Appl Immunol. 1980;61(2):150-8. doi: 10.1159/000232428.
PMID:7351347
Abstract
Aspirin (acetylsalicylic acid), ASA and sodium salicylate (NaSA) activate the complement system in vitro. The activation involves the components of the classical pathway. It is, however, antibody independent. Evidence for activation are (1) consumption of C and C component activities; (2) activation of C1 evidenced by release of C1s from the macromolecular complex, and (3) C3 and C5 conversion.
摘要
阿司匹林（乙酰水杨酸）、ASA 和水杨酸钠（NaSA）在体外可激活补体系统。这种激活涉及经典途径的成分。然而，它不依赖抗体。激活的证据包括：（1）C 和 C 成分活性的消耗；（2）从大分子复合物中释放 C1s 证明 C1 被激活；以及（3）C3 和 C5 的转化。
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