Thiery M, Parewyck W, De Gezelle H, van Kets H, Smis B, Verheugen C, Gerris J, Voorhoof L, Derom R, Martens G
Z Geburtshilfe Perinatol. 1978 Oct;182(5):352-7.
Pre-induction ripening of the unfavorable cervix was attempted in 104 normal term gravidas by means of a single extra-amniotic instillation of a viscous gel containing 0.5 mg prostaglandin E2. The procedure was highly successful and no adverse effect on mother or fetus was observed.