Alwmark A, Andersson A, Lasson A
Ann Surg. 1980 Jan;191(1):13-8. doi: 10.1097/00000658-198001000-00003.
Sixty-six patients with primary adenocarcinomas of the duodenum recorded by the Swedish Cancer Register during 1958-1973 are reviewed. The mean age was 66 years, and female:male ratio 1.2:1.0. The predominant symptom was duodenal obstruction. Correct diagnosis was made in 68% by conventional barium meal examination. Hypoton duodenography and duodenoscopy are necessary diagnostic aids. In 25% of the patients the diagnosis was first made at postmortem examination. Thirty-two patients had metastases at first diagnosis. Forty-three per cent were radically operated and 43% palliatively. The operative mortality after curative operations was 25% with no difference correlated to operative methods with the exception of pure polyp extirpation where no patient died. The overall one-year survival was 67% and five-year 18%. There was a tendency for longer survival time for patients with more distally situated carcinomas. Duodenopancreatectomy gave a longer survival time than duodenal resection.
对瑞典癌症登记处1958年至1973年间记录的66例十二指肠原发性腺癌患者进行了回顾性研究。平均年龄为66岁，女性与男性比例为1.2:1.0。主要症状为十二指肠梗阻。传统钡餐检查对68%的患者做出了正确诊断。低张十二指肠造影和十二指肠镜检查是必要的诊断辅助手段。25%的患者在尸检时才首次确诊。32例患者在首次诊断时已有转移。43%的患者接受了根治性手术，43%接受了姑息性手术。根治性手术后的手术死亡率为25%，除单纯息肉摘除术无一例死亡外，与手术方式无关。总体一年生存率为67%，五年生存率为18%。癌肿位置越靠远端的患者生存时间有延长的趋势。十二指肠胰头切除术的生存时间比十二指肠切除术长。
