乙基乙酰丙烯酸酯（一种巯基试剂和细胞松弛素A的潜在类似物）对微管蛋白组装的抑制作用。
Inhibition of tubulin assembly by ethylacetylacrylate, a sulfhydryl reagent and potential analog of cytochalasin A.
作者信息
Himes R H, Himes V B
出版信息
Biochim Biophys Acta. 1980 Feb 27;621(2):338-42. doi: 10.1016/0005-2795(80)90186-5.
PMID:7353048
Abstract
Ethyl acetylacrylate reacts rapidly with 2-mercaptoethanol and the sulfhydryl groups of tubulin. The structure of ethyl acetylacrylate resembles that of the reactive portion of cytochalasin A and potentially can serve as an analog of this antibiotic.
摘要
乙酰丙烯酸乙酯能迅速与2-巯基乙醇及微管蛋白的巯基发生反应。乙酰丙烯酸乙酯的结构类似于细胞松弛素A的反应部分，并且有可能作为这种抗生素的类似物。
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