Egeberg K, Helgeland L
Biochim Biophys Acta. 1980 Feb 7;627(3):225-9. doi: 10.1016/0304-4165(80)90451-1.
The distribution of vitamin K epoxidase activity in rough and smooth microsomes has been studied and compared to the prothrombin precursor and vitamin K-dependent carboxylase activity. All three activities were high in rough microsomes as compared to the low levels found in smooth microsomes. The results are in agreement with the suggestion that there might be a linkage between the vitamin K-dependent carboxylation and epoxidation reaction in vivo.
对粗糙型和光滑型微粒体中维生素K环氧化酶活性的分布进行了研究，并与凝血酶原前体和维生素K依赖性羧化酶活性进行了比较。与光滑型微粒体中发现的低水平相比，所有这三种活性在粗糙型微粒体中都很高。这些结果与体内维生素K依赖性羧化和环氧化反应之间可能存在联系的观点一致。
