Klein E, Schwartz R A, Laor Y, Milgrom H, Burgess G H, Holtermann O A
Cancer. 1980 Feb;45(3):427-31. doi: 10.1002/1097-0142(19800201)45:3<427::aid-cncr2820450304>3.0.co;2-1.
Fourteen patients with Kaposi's sarcoma (KSY were treated systemically with vinblastine sulfate in a low-dose regimen and compared with 23 patients reported in the medical literature. The therapeutic results in our series were excellent in terms of regression of cutaneous lesions. Vinblastine appears to be a drug that is well suited for the management of KS in an outpatient setting. Intravenous therapy may be supplemented with intralesional or intraarterial vinblastine.
14例卡波西肉瘤(KS)患者接受了低剂量硫酸长春碱全身治疗,并与医学文献报道的23例患者进行了比较。就皮肤病变的消退而言,我们系列中的治疗结果非常出色。长春碱似乎是一种非常适合在门诊环境中治疗KS的药物。静脉治疗可以辅以瘤内或动脉内注射长春碱。