Schiff B L, Kern A B
Cutis. 1980 Jan;25(1):88-9.
Elephantiasis nostras is one of the most striking yet, at the same time, one of the most poorly understood dermatologic entities. We present a report on two patients with this disorder, each of whom had a marked enlargement of a lower extremity following recurrent attacks of infection and/or ulceration. In one case obesity and chronic cardiac disease may have been aggravating factors. In the second, the enlargement and deformity was severe enough to require amputation of the foot and lower leg. Study of these and other cases may lead to further insight into the pathogenesis of elephantiasis nostras.
nostras象皮病是最显著的皮肤病之一,但同时也是了解最少的皮肤病之一。我们报告了两名患有这种疾病的患者,他们每人在反复感染和/或溃疡发作后下肢都有明显肿大。在一个病例中,肥胖和慢性心脏病可能是加重因素。在第二个病例中,肿大和畸形严重到需要截肢足部和小腿。对这些病例和其他病例的研究可能会进一步深入了解nostras象皮病的发病机制。