pH对酶催化反应的影响：一个根据动力学数据确定酶可电离基团pK值的计算机程序。
The effect of pH on enzyme-catalysed reactions: a computer program to determine pK values of enzyme ionisable groups from kinetic data.
作者信息
Gregory R B, Kinderlerer J
出版信息
Int J Biomed Comput. 1980 Jan;11(1):53-66. doi: 10.1016/0020-7101(80)90006-9.
PMID:7353919
Abstract
The paper describes a non-linear multiple regression program to analyse the kinetic parameters Vm and Km as functions of pH, assuming that the activity of particular enzyme forms is determined by the ionisation of two groups, the active form of the enzyme being the half-ionised species.
摘要
本文描述了一个非线性多元回归程序，用于分析动力学参数Vm和Km作为pH值的函数，假设特定酶形式的活性由两组离子化作用决定，酶的活性形式为半离子化物种。
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