Amino-acid neighborhood relationships in proteins. Breakdown of amino-acid sequences into overlapping doublets, triplets and quadruplets.

A method has been developed which allows the breakdown of an amino-acid sequence of proteins into overlapping di-, tripeptides, etc. The frequency of their distribution provides very convincing evidence that these sequences are non-random. These peptides have been demonstrated to be capable of being used as an objective key for the classification of organisms, and of proteins. It is also believed that they can be useful in increasing the accuracy of the prediction of protein folding.