Davidson J N, Hirsh D C
J Am Vet Med Assoc. 1980 Jan 15;176(2):124-5.
Two major episodes of acute hemolytic disease in lambs were associated with high mortality. Clinical signs were severe depression, dyspnea, and tachycardia. Gross postmortem findings included hemoglobinuria and icterus. Histologic examination revealed tubular necrosis and periacinar hepatocellular necrosis. Leptospira interrogans serotype pomona was proposed as the causative agent because high serum antibody titers for this bacterium were found in lambs and ewes in the affected flocks.
羔羊急性溶血性疾病的两次主要发作与高死亡率相关。临床症状为严重抑郁、呼吸困难和心动过速。尸检大体所见包括血红蛋白尿和黄疸。组织学检查显示肾小管坏死和腺泡周围肝细胞坏死。由于在受影响羊群的羔羊和母羊中发现了针对该细菌的高血清抗体滴度，因此推测问号钩端螺旋体波摩那群是病原体。
