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[肾脏保存装置(实验室模型LM 1和LM 2)及其组件的设计与构建]

[Design and construction of a kidney preservation unit (Laboratory Models LM 1 and LM 2) and its components].

作者信息

Schabel J, Pauer H D, Brettschneider G

出版信息

Z Urol Nephrol. 1978 Oct;71(10):757-62.

PMID:735470
Abstract

By combination of the adequate construction elements (cryostate, warmth exchanger, roll pump) the laboratory model of unit for the preservation of kidneys for animal experimental investigations was established. For this purpose a special organ container made of piacryl was constructed in two models, which with double walls does not need a particular isolation and, therefore, is freely accessible for manipulations during the experiment. Measurings of the horizontal and vertical distribution of the temperature in the organ container resulted in a decrease of temperature of 5--6 degrees (single bottom of the container) or 1--2 degrees (double chilled bottom of the container). The report of the courses of temperature during an organ perfusion resulted in a constancy of the average temperature of 6--8 degrees. The kidney preservation unit has proved in a long-term experiment during 24 hours.

摘要

通过组合适当的构建元件(低温状态、热交换器、滚压泵),建立了用于动物实验研究的肾脏保存单元的实验室模型。为此,用有机玻璃制作了两种型号的特殊器官容器,其双壁结构不需要特殊隔离,因此在实验过程中便于操作。对器官容器内温度的水平和垂直分布进行测量,结果表明,容器单层底部温度下降5 - 6度,双层冷却底部温度下降1 - 2度。器官灌注过程中的温度变化报告显示,平均温度保持在6 - 8度恒定。肾脏保存单元在长达24小时的长期实验中得到了验证。

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