Sherman R A, Blaufox M D
Nephron. 1980;25(2):82-6. doi: 10.1159/000181758.
A retrospective review of 27 patients with nonvisualization on 131I-orthoiodohippurate (Hippuran) renal scan during 1972--1977 was carried out. 5 patients had renal failure caused by urinary tract obstruction and of these, 4 were submitted to surgical relief. Varying levels of life-sustaining renal function were recovered in all 4 patients. 16 had chronic intrinsic renal disease, of whom 7 were admitted for reasons not directly related to renal failure. All of these required chronic dialysis within 3--6 months. The remaining 7 patients had acute renal failure (clinically, acute tubular necrosis) and none of them survived. It had been well established that the prognosis for recoverability of renal function is extremely poor in patients with nonvisualization on hippuran scan. It is important, therefore, to emphasize that nonvisualization on 131I-orthoiodohippurate renal scan in patients with urinary tract obstruction does not exclude the potential for recoverable renal function. Therefore, even in the absence of renal visualization, the need to definitively rule out urinary tract obstruction remains.
对1972年至1977年间27例在131I - 邻碘马尿酸（Hippuran）肾扫描中不显影的患者进行了回顾性研究。5例患者因尿路梗阻导致肾衰竭，其中4例接受了手术解除梗阻。所有4例患者均恢复了不同程度的维持生命的肾功能。16例患有慢性肾实质疾病，其中7例因与肾衰竭无直接关系的原因入院。所有这些患者均在3至6个月内需要进行慢性透析。其余7例患者患有急性肾衰竭（临床上为急性肾小管坏死），无一存活。 Hippuran扫描不显影的患者肾功能恢复的预后极差，这一点已得到充分证实。因此，必须强调，尿路梗阻患者131I - 邻碘马尿酸肾扫描不显影并不排除肾功能可恢复的可能性。因此，即使没有肾脏显影，也仍然需要明确排除尿路梗阻。
