99mTc-P-丁基-IDA与131I-孟加拉玫瑰红闪烁扫描术在新生儿黄疸中的联合应用
Simultaneous 99mTc-P-butyl-IDA and 131I-rose bengal scintigraphy in neonatal jaundice.
作者信息
Collier B D, Treves S, Davis M A, Heyman S, Subramanian G, McAfee J G
出版信息
Radiology. 1980 Mar;134(3):719-22. doi: 10.1148/radiology.134.3.7355225.
Eight neonates with jaundice were studied simultaneously with 99mTc-p-butyl-IDA and 131I-rose bengal. Due to physical decay, 99mTc-p-butyl-IDA failed to demonstrate delayed excretion through the patent extrahepatic biliary tract in 3 of 5 patients with concomitant hepatitis; 131I-rose bengal showed small-bowel activity in all 5. Neither agent demonstrated small-bowel activity in 3 neonates with extrahepatic biliary atresia. Based on this clinical trial, 131I-rose bengal remains the radiopharmaceutical of choice for distinguishing between hepatitis and biliary atresia in these patients.
对8例黄疸新生儿同时使用99mTc - 对丁基IDA和131I - 孟加拉玫瑰红进行研究。由于物理衰变，99mTc - 对丁基IDA未能在5例合并肝炎的患者中的3例中显示出通过开放的肝外胆道的延迟排泄；131I - 孟加拉玫瑰红在所有5例中均显示出小肠活性。两种药物在3例肝外胆道闭锁的新生儿中均未显示出小肠活性。基于这项临床试验，131I - 孟加拉玫瑰红仍然是区分这些患者肝炎和胆道闭锁的首选放射性药物。
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