甲羟孕酮在转移性肾细胞癌中的应用
Medroxyprogesterone in metastatic renal cell carcinoma.
作者信息
Rao M K, Soloway M S
出版信息
South Med J. 1980 Feb;73(2):247-8. doi: 10.1097/00007611-198002000-00034.
Abstract
We have described a patient in whom complete regression of pulmonary metastases from renal cell carcinoma (RCC) followed treatment with medroxy-progesterone acetate (Depo-Provera). Although the reported rate of objective response to progesterone therapy in RCC is only 10% to 15%, the occasionally dramatic results, especially in men, warrant a trial of this agent. Other more toxic agents have consistently failed to provide significant responses.
摘要
我们描述了一名肾细胞癌（RCC）肺转移患者，其在接受醋酸甲羟孕酮（Depo - Provera）治疗后肺转移灶完全消退。尽管报道的RCC患者对孕酮治疗的客观缓解率仅为10%至15%，但其偶尔出现的显著效果，尤其是在男性患者中，值得对该药物进行试验。其他毒性更强的药物一直未能产生显著疗效。
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