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术后胃霉菌病

Postoperative gastric mycosis.

作者信息

Konok G, Haddad H, Strom B

出版信息

Surg Gynecol Obstet. 1980 Mar;150(3):337-41.

PMID:7355357
Abstract

Significant symptoms postoperatively may be associated with massive growth of yeast organisms in the gastric remnant. Contrary to reports in the literature, the roentgenologic appearance is suggestive but not diagnostic of the presence of gastric mycosis. In our series, roentgenologic studies, gastroscopy and direct microscopic examination of the gastric contents have been required to establish the diagnosis of gastric mycosis. In our experience, as well as in that of other reported series, gastric mycosis has been most frequently seen following vagotomy and antrectomy with Billroth I reconstruction. The physiopathology is speculative, but abnormal gastric emptying of solids, increased intragastric pH and reflux of duodenal contents into the stomach are strongly suggestive factors. Treatment of this condition, as reported in the literature, has been empiric and not quite successful. Our treatment protocol has given us more satisfactory results. Postoperatively, gastric mycosis is a benign condition not associated with obstruction of the gastric outlet or the intestine, gastric hemorrhage, anemia or peforation. Aggressive treatment is not justified in the absence of severe symptoms. If the reflux of duodenal contents is suspected to be an important contributing factor, reconstruction of the gastric outlet using the Roux-en-Y principle may give gratifying results.

摘要

术后显著症状可能与胃残余部酵母菌大量生长有关。与文献报道相反,X线表现有提示作用,但不能诊断胃霉菌病。在我们的系列病例中,需要进行X线检查、胃镜检查及胃内容物直接显微镜检查来确诊胃霉菌病。根据我们的经验以及其他报道的系列病例,胃霉菌病最常见于迷走神经切断术和毕Ⅰ式胃大部切除术后。其生理病理学机制尚属推测,但固体食物胃排空异常、胃内pH值升高以及十二指肠内容物反流至胃内是强烈的提示性因素。据文献报道,对此病的治疗一直是经验性的,且不太成功。我们的治疗方案取得了更令人满意的结果。术后,胃霉菌病是一种良性疾病,与胃出口或肠道梗阻、胃出血、贫血或穿孔无关。在没有严重症状的情况下,积极治疗并不合理。如果怀疑十二指肠内容物反流是一个重要的促成因素,采用Roux-en-Y原则重建胃出口可能会取得满意的效果。

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