Nephrogenic adenoma of urinary bladder associated with malakoplakia.

A case of nephrogenic adenoma occurring in a twelve-year-old black female child, associated with recurrent Escherichia coli urinary tract infection is described. The patient was followed for over six years and treated with repeated cystoscopic examinations and fulgurations of the lesion. Five years after the initial diagnosis, malakoplakia of the bladder developed in association with nephrogenic adenoma. There was no evidence of invasion of the bladder by the lesion during these six years. Electron microscopic study of nephrogenic adenoma indicated its origin from the urothelium. Nephrogenic adenoma of the bladder is to be considered as a benign metaplastic lesion of the urothelium and is to be treated with repeated cystoscopic fulgurations.