Morrison J A, Khoury P, Kelly K, Mellies M J, Parrish E, Heiss G, Tyroler H, Glueck C J
Am J Epidemiol. 1980 Feb;111(2):156-65. doi: 10.1093/oxfordjournals.aje.a112883.
Systolic blood pressure (SBP) and diastolic blood pressure (DBP), along with demographic and anthropometric variables were assessed in a biracial group of schoolchildren and parents in an integrated suburban school district: 682 schoolchildren, ages 6--19, including 268 white males, 236 white females, 85 black males and 93 black females; 362 adults, ages 20--64, including 142 white males, 159 white females, 20 black males and 41 black females. There were no significant black-white SBP or DBP differences in children, while SBP and DBP were higher in adult blacks than whites. Using multiple regression analysis, with BP as the dependent variable, SBP in children was significantly associated with pulse, weight, skinfold thickness, age and height; DBP was significantly associated with age, pulse, weight, and skinfold thickness. Race, sex, and education of the head of household did not significantly enter the multiple regression matrix for children's BP. Respectively, 29% and 22% of the variance of the children's SBP and DBP was accounted for by the measured variables. In adults, SBP was significantly related to weight, race, pulse, and age; DBP was significantly related to weight, race, age, and skinfold thickness. Respectively, 27% and 24% of the variance of the adults' SBP and DBP was accounted for by the measured variables. Covariance adjusted mean SBP and DBP were higher in hypertriglyceridemic than in hypotriglyceridemic children (p = 0.001), and were lower in hyperalpha-lipoproteinemic than hypoalpha-lipoproteinemic children (p less than or equal to 0.03). Children in an integrated school district may have shared behaviors, goals, and environments contributing to shared BP, while differing environmental factors may become amplified with age and life experience and contribute to higher BP in black adults.
在一个城郊一体化学区的不同种族学童和家长群体中，对收缩压（SBP）、舒张压（DBP）以及人口统计学和人体测量学变量进行了评估：682名6至19岁的学童，包括268名白人男性、236名白人女性、85名黑人男性和93名黑人女性；362名20至64岁的成年人，包括142名白人男性、159名白人女性、20名黑人男性和41名黑人女性。儿童中黑人和白人的收缩压或舒张压没有显著差异，而成年黑人的收缩压和舒张压高于白人。使用多元回归分析，以血压作为因变量，儿童的收缩压与脉搏、体重、皮褶厚度、年龄和身高显著相关；舒张压与年龄、脉搏、体重和皮褶厚度显著相关。种族、性别和户主的教育程度在儿童血压的多元回归模型中没有显著作用。所测量的变量分别解释了儿童收缩压和舒张压方差的29%和22%。在成年人中，收缩压与体重、种族、脉搏和年龄显著相关；舒张压与体重、种族、年龄和皮褶厚度显著相关。所测量的变量分别解释了成年人收缩压和舒张压方差的27%和24%。高甘油三酯血症儿童的协方差调整后的平均收缩压和舒张压高于低甘油三酯血症儿童（p = 0.001），高α脂蛋白血症儿童的则低于低α脂蛋白血症儿童（p≤0.03）。在一体化学区的儿童可能有共同的行为、目标和环境，这有助于形成共同的血压水平，而不同的环境因素可能随着年龄和生活经历而放大，导致成年黑人血压升高。
