Takahashi K, Diamond F, Bieniarz J, Yen H, Burd L
Am J Obstet Gynecol. 1980 Mar 15;136(6):774-9. doi: 10.1016/0002-9378(80)90455-x.
The records of 117 patients who had serial nonstress tests (N = 285) and oxytocin challenge tests (N = 268) were analyzed to determine whether baseline uterine contractility and/or oxytocin sensitivity changed with increasing gestational age. The results obtained in patients who were delivered before, at, and after term were compared. Uterine contractility and oxytocin sensitivity increased in all groups as gestational age progressed. No significant differences in uterine contractility were noted among groups; however, oxytocin sensitivity was significantly increased in the preterm group (p less than 0.001) and decreased in the postterm group (p less than 0.001). Our results suggest that the response of the uterus to oxytocin early in pregnancy may help to identify patients who will be delivered before or after term.
分析了117例接受系列无应激试验（N = 285）和缩宫素激惹试验（N = 268）患者的记录，以确定基线子宫收缩力和/或缩宫素敏感性是否随孕周增加而变化。比较了在足月前、足月时和足月后分娩患者的结果。随着孕周进展，所有组的子宫收缩力和缩宫素敏感性均增加。各组间子宫收缩力无显著差异；然而，早产组缩宫素敏感性显著增加（p<0.001），过期产组缩宫素敏感性降低（p<0.001）。我们的结果表明，妊娠早期子宫对缩宫素的反应可能有助于识别将在足月前或足月后分娩的患者。
