Józsa L, Renner A, Sántha E
Acta Chir Acad Sci Hung. 1978;19(2):149-56.
Specimens of the affected muscles obtained during reconstructive surgery 4 to 16 weeks after injury of the tendon or of the motor nerve of the human hand were studied. After tenotomy the most serious lesions were displayed by the contractile elements which were homogeneous brittle and atrophied, and disintegrated independently of the functional units. The number of mitochondria decreased, the sarcoplasmic reticulum accumulated and the red and white muscle fibres could not be distinguished. After motor nerve injury the motor end plates were completely destroyed and Wallerian degeneration appeared. The contractile elements atrophied and were brittle. The number of mitochondria and the sarcoplasmic reticulum decreased, the sarcoplasmic glycogen content was higher than normal, and often the cell nuclei occupied a central position.
对人类手部肌腱或运动神经损伤后4至16周进行重建手术时获取的受影响肌肉标本进行了研究。切断肌腱后，收缩元件出现最严重的病变，这些元件均质、易碎且萎缩，并独立于功能单位解体。线粒体数量减少，肌浆网积聚，红色和白色肌纤维无法区分。运动神经损伤后，运动终板完全破坏，出现华勒变性。收缩元件萎缩且易碎。线粒体和肌浆网数量减少，肌浆糖原含量高于正常，细胞核常占据中心位置。
